Español24/7 enrollment line386-218-5911
Open studies

What is enrolling now.

Pick the one closest to your health situation. Each page lists who can join, how long it runs, and what the visits look like.

Type 2 Diabetes with Obesity, clinical trial in Orange City, FL
EnrollingEndocrinology

Type 2 Diabetes with Obesity

Evaluating a new investigational therapy for adults with Type 2 Diabetes and obesity, measuring weight loss, metabolic health, and glycemic control.

See eligibility →
COPD with Type 2 Inflammation, clinical trial in Orange City, FL
EnrollingPulmonology

COPD with Type 2 Inflammation

Testing Depemokimab, an investigational long-acting anti-IL-5 therapy, to reduce exacerbations in adults with moderate-to-severe COPD.

See eligibility →
Idiopathic Short Stature (ISS) Growth Study, clinical trial in Orange City, FL
EnrollingPediatric Endocrinology

Idiopathic Short Stature (ISS) Growth Study

Evaluating Vosoritide, an investigational therapy designed to support bone growth and improve height outcomes in children with Idiopathic Short Stature.

See eligibility →
Major Depressive Disorder: Relapse Prevention, clinical trial in Orange City, FL
EnrollingPsychiatry

Major Depressive Disorder: Relapse Prevention

Testing Brenipatide alongside standard antidepressant therapy to delay or prevent relapse in adults currently in remission from MDD.

See eligibility →
Adults Living with Obesity (Without Diabetes), clinical trial in Orange City, FL
Actively RecruitingMetabolic Health

Adults Living with Obesity (Without Diabetes)

Clinical research evaluating weight management for adults living with obesity who do not have a diabetes diagnosis.

See eligibility →
Type 2 Diabetes with Overweight or Obesity (VESPER-5), clinical trial in Orange City, FL
EnrollingEndocrinology

Type 2 Diabetes with Overweight or Obesity (VESPER-5)

A Phase 3 study (VESPER-5) of an investigational ultra-long-acting GLP-1 receptor agonist for adults with overweight or obesity and Type 2 Diabetes.

See eligibility →
Type 2 Diabetes with Obesity (AMAZE 8), clinical trial in Orange City, FL
EnrollingEndocrinology

Type 2 Diabetes with Obesity (AMAZE 8)

An investigational treatment study (AMAZE 8) for adults living with Type 2 Diabetes and overweight or obesity.

See eligibility →
Tardive Dyskinesia, clinical trial in Orange City, FL
EnrollingNeurology

Tardive Dyskinesia

A clinical research study of an investigational treatment for adults with tardive dyskinesia, involuntary, repetitive movements often linked to long-term use of certain psychiatric medications.

See eligibility →
Tardive Dyskinesia: Valbenazine Study, clinical trial in Orange City, FL
EnrollingNeurology

Tardive Dyskinesia: Valbenazine Study

A Phase 4, open-label study of valbenazine for adults with tardive dyskinesia who remain symptomatic on deutetrabenazine or after stopping a prior VMAT2 inhibitor.

See eligibility →
Where we are

Orange City, between Orlando and Daytona.

Our main research site is at 2541 South Volusia Ave., Suite 100, Orange City, FL 32763. People drive in from Orange City, Deltona, DeBary, DeLand, Lake Helen, Sanford, Lake Mary, Orlando, and Daytona Beach. If you are not sure whether you are close enough, call and ask. We would rather tell you straight than have you guess.

We also run a Phase I inpatient unit in DeBary and a psychiatry and neurology location, Medical Research Group of Central Florida, in Orange City. See all three locations.

Get directions ↗

Pre-qualify

See if you qualify.

A study coordinator calls you within one business day. No cost. No obligation.

FreeMedical care & study drug
PaidTime & travel reimbursement
SafeIRB-reviewed protocols
Pre-qualify in 60 seconds

See if you qualify for a study.

No cost. No obligation. A study coordinator will call you within one business day.

Or call 386-218-5911

Your information is used only to contact you about clinical research opportunities at Optimal Research Sites. We do not share data with third parties. See our privacy policy.

Common questions

Before you call.

How do I find clinical trials near me?
Start with the list on this page. Every study here runs at our Orange City, FL site (2541 South Volusia Ave., Suite 100). If one looks close to your situation, fill out the short pre-qualification form or call 386-218-5911. A study coordinator checks the basics with you and calls back within one business day.
How far will I have to drive?
Most people who enroll live within about 30 minutes of Orange City. We see participants from Orange City, Deltona, DeBary, DeLand, Lake Helen, Sanford, Lake Mary, Orlando, Daytona Beach. Visits are by appointment Monday to Friday, 8a to 5p ET.
What does it cost to take part?
Nothing. Study visits, investigational medication, and study-related labs are covered by the study sponsor, not your insurance. Participants are reimbursed for time and travel, and the amount depends on the study.
Do you have Spanish-speaking staff?
Yes. Our study team is bilingual in English and Spanish, and there is a Spanish version of the site at /es.
Are these studies approved and registered?
Every study is reviewed by an independent Institutional Review Board (IRB) and run under FDA-regulated Good Clinical Practice standards. Each study page links its ClinicalTrials.gov record so you can look it up yourself.