Clinical trials near me, in Central Florida.
If you are searching for clinical trials near you, Optimal Research Sites has 9 studies open right now at our site in Orange City, FL, about 30 minutes from most of Volusia and Seminole counties. Study care and investigational medication cost you nothing, and you are paid for your time and travel.
What is enrolling now.
Pick the one closest to your health situation. Each page lists who can join, how long it runs, and what the visits look like.

Type 2 Diabetes with Obesity
Evaluating a new investigational therapy for adults with Type 2 Diabetes and obesity, measuring weight loss, metabolic health, and glycemic control.
See eligibility →
COPD with Type 2 Inflammation
Testing Depemokimab, an investigational long-acting anti-IL-5 therapy, to reduce exacerbations in adults with moderate-to-severe COPD.
See eligibility →
Idiopathic Short Stature (ISS) Growth Study
Evaluating Vosoritide, an investigational therapy designed to support bone growth and improve height outcomes in children with Idiopathic Short Stature.
See eligibility →
Major Depressive Disorder: Relapse Prevention
Testing Brenipatide alongside standard antidepressant therapy to delay or prevent relapse in adults currently in remission from MDD.
See eligibility →
Adults Living with Obesity (Without Diabetes)
Clinical research evaluating weight management for adults living with obesity who do not have a diabetes diagnosis.
See eligibility →
Type 2 Diabetes with Overweight or Obesity (VESPER-5)
A Phase 3 study (VESPER-5) of an investigational ultra-long-acting GLP-1 receptor agonist for adults with overweight or obesity and Type 2 Diabetes.
See eligibility →
Type 2 Diabetes with Obesity (AMAZE 8)
An investigational treatment study (AMAZE 8) for adults living with Type 2 Diabetes and overweight or obesity.
See eligibility →
Tardive Dyskinesia
A clinical research study of an investigational treatment for adults with tardive dyskinesia, involuntary, repetitive movements often linked to long-term use of certain psychiatric medications.
See eligibility →
Tardive Dyskinesia: Valbenazine Study
A Phase 4, open-label study of valbenazine for adults with tardive dyskinesia who remain symptomatic on deutetrabenazine or after stopping a prior VMAT2 inhibitor.
See eligibility →Orange City, between Orlando and Daytona.
Our main research site is at 2541 South Volusia Ave., Suite 100, Orange City, FL 32763. People drive in from Orange City, Deltona, DeBary, DeLand, Lake Helen, Sanford, Lake Mary, Orlando, and Daytona Beach. If you are not sure whether you are close enough, call and ask. We would rather tell you straight than have you guess.
We also run a Phase I inpatient unit in DeBary and a psychiatry and neurology location, Medical Research Group of Central Florida, in Orange City. See all three locations.
See if you qualify.
A study coordinator calls you within one business day. No cost. No obligation.